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Toradol ketorolac tromethamine is a registered trademark of hoffmann-la roche inc.

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A history of asthma or a severe allergic reaction after taking aspirin or an NSAID;

Do not use this medicine just before or after heart bypass surgerycoronary artery bypass graftor CABG

Every effort has been made to ensure that the information provided by Cerner MultumIncMultumis accurateup-to-dateand completebut no guarantee is made to that effectDrug information contained herein may be time sensitiveMultum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriateunless specifically indicated otherwiseMultum’s drug information does not endorse drugsdiagnose patients or recommend therapyMultum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement toand not a substitute forthe expertiseskillknowledge and judgment of healthcare practitionersThe absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safeeffective or appropriate for any given patientMultum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum providesThe information contained herein is not intended to cover all possible usesdirectionsprecautionswarningsdrug interactionsallergic reactionsor adverse effectsIf you have questions about the drugs you are takingcheck with your doctornurse or pharmacist.

ToradolKetorolacis currently used by many surgeons as adjuvant therapy in addition to standard narcotics in managing immediate postoperative painToradolKetorolacis a non-steroidal anti-inflammatory drug that acts as a non-selective cyclooxygenaseCOXinhibiting COX-1 and COX-2 isoformsToradolKetorolac has been associated with significant complications including postoperative bleeding and acute renal insufficiencyCelebrexCelecoxibis a selective COX-2 inhibitor that has been associated with adverse cardiovascular outcomes in patients with pre-existing cardiac disease but not with postoperative bleeding or renal insufficiencyCelebrexCelecoxibhas also been shown to control postoperative pain but has never been compared to ToradolKetorolac

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