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Pancreatitishepatotoxicityand peripheral neuropathy have occurred when hydroxyurea was administered concomitantly with antiretroviral drugsincluding didanosine and stavudinesee DRUG INTERACTIONS

Since this drug can be absorbed through the skin and lungswomen who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the tablets/capsules.

Use of hydroxyurea with didanosineVidexVidex ECwith or without stavudineZeritZerit XRhas been associated with an increased incidence of side effects including pancreatitis and peripheral neuropathynerve problemsIn generalhydroxyurea is not recommended in HIV patients as decreased CD4 countsdecreased viral suppressionand increased risk of side effects has been reported.

Hydroxyurea oral capsule is available as the brand-name drugs Hydrea and DroxiaHydrea is also available as a generic drugDroxia is notGeneric drugs usually cost less than the brand-name versionIn some casesthey may not be available in every strength or form as the brand-name drug.

Tell your doctor right away if you have any serious side effectsincludingskin problemssuch as ulcersdarkened/blackened/reddened skinmental/mood changessuch as confusionhallucinationsseizuresshortness of breathchest painsigns of kidney problemssuch as change in the amount of urine

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