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Domperidone motilium is the anti-sickness drug of choice to prevent and treat nausea and vomiting caused by levodopa.

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Reasonable care has been taken to provide accurate information at the time of creationThis information is not intended to substitute medical advicediagnosis or treatment and should not be exclusively relied on to manage or diagnose a medical conditionPlease refer to our terms and conditions.

Separate in vivo pharmacokinetic/pharmacodynamic interaction studies with oral ketoconazole or oral erythromycin in healthy subjects confirmed a marked inhibition of domperidone’s CYP3A4 mediated first pass metabolism by these drugs.

Domperidone is associated with a small increased risk of serious cardiac side effectsThe UK Commission on Human MedicinesCHMhas concluded that products containing domperidone meet the requirements for prescription-only supplyTherefore people need to have a medical assessment before taking domperidone to determine if it is suitable for them.

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