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The potential for drug interactions for keppra xr is expected to be essentially the same as that with immediate-release keppra tablets.

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The use of levetiracetam has been very rarely associated with acute kidney injurywith a time to onset ranging from a few days to several months.

Get emergency medical help if you have any of these signs of an allergic reactionhivesdifficult breathingswelling of your facelipstongueor throat.

KEPPRA may cause behavioral abnormalities and psychotic symptomsPatients treated with KEPPRA should be monitored for psychiatric signs and symptoms.

There is no specific antidote for overdose with KEPPRAIf indicatedelimination of unabsorbed drug should be attempted by emesis or gastric lavageusual precautions should be observed to maintain airwayGeneral supportive care of the patient is indicated including monitoring of vital signs and observation of the patient’s clinical statusA Certified Poison Control Center should be contacted for up to date information on the management of overdose with KEPPRA.

The administration of levetiracetam to patients with renal impairment may require dose adjustmentIn patients with severely impaired hepatic functionassessment of renal function is recommended before dose selectionsee section 4.2

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